Hoagland Sign: An early manifestation of acute infectious mononucleosis - A case report
نویسنده
چکیده
Infectious Mononucleosis (IM) is the clinical syndrome caused by Epstein-Barr Virus (EBV). Originally described as glandular fever, it derives its name from the mononuclear lymphocytosis with atypical-appearing lymphocytes that accompany the illness [1]. It is characterized by systemic complaints consisting primarily of fatigue, malaise, fever, sore throat, and generalized lymphadenopathy. The presence of “Hoagland Sign”, i.e., early and transient edema of upper eyelids in IM is a less common clinical feature [2]. Its presence can be an important clue in diagnosis of IM caused by EBV. A case of an eight-anda-half year old girl with Hoagland Sign in IM is reported.
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